Aug 2026· Computational biology and chemistry· Vol 125, pp.
109310
· 0 citations
Medicine
TL;DR
A novel molecular representation learning framework, termed SMFP, which integrates self-supervised learning and multimodal feature fusion, and incorporates a bidirectional cross-attention module for feature fusion, enabling the framework to better capture the relevance and importance of different molecular modalities and to more effectively integrate multimodal feature information.
A novel multimodal alignment framework for joint modeling of molecular graphs and sequences, called Mol-ME, which employs ensemble learning to predict on extracted representations, which captures complex nonlinear relationships and compensates for the modeling limitations of single shallow networks.
Bao-Ren Huang, Mu Chen, Jun-Jie Luo et al.· Journal of Chemical Informat...· 0 citations
GSSCMI is innovatively design an efficient co-attention mechanism that simultaneously modulates fused modalities through unified and fine-grained attention scores, achieving balanced fusion while significantly reducing computational overhead.
Lihao Sun, Xin Wang, Fang Wang et al.· IEEE journal of biomedical a...· 0 citations
By holistically integrating atomic, motif, and global fingerprint information via hypergraph modeling, HyperMolFusion offers a more reliable computational tool to enhance the efficiency and accuracy of drug development pipelines.
Yawen Lin, Sheng Lian, Shaoxin Bian et al.· IEEE journal of biomedical a...· 1 citation
MG-CMIF is developed, a multi-granularity cross-modal framework for molecular property prediction that achieves better prediction results than competitive methods in both classification and regression settings and confirms that hierarchical structural modeling and cross-view integration both contribute to the effective...
Qun Liu, Mao-Yuan Zang, Rui Han et al.· Journal of Machine Learning...· 0 citations
MOTIVATION
Self-supervised pre-training models for molecular data have demonstrated notable results across many downstream tasks. The inherent multimodal properties of molecules have also motivated efforts to capture information from different modalities. However, current multimodal molecular pre-training models usuall...
Kang-Jie Zheng, Jun-Wei Yang, Siyu Long et al.· Bioinformatics· 0 citations