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Open access Aug 2026

Cerium molybdate-doped polyaniline nanoplatform for GSH-depletion-enhanced chemodynamic/NIR-II photothermal synergistic therapy via ferroptosis and immune activation

Cerium molybdate-doped polyaniline nanoparticles are developed to enable a synergistic combination of photothermal therapy (PTT) and CDT, thereby triggering immunogenic cell death (ICD) and enhancing antitumor immunity and presenting a robust nanoplatform integrating chemodynamic and photothermal therapies for potent c...

Yulin Kuang, Cheng Lu, Bo-Lan Yu et al. · 0 citations
Aug 2026

Combining H2O2-Supplying Iron Peroxide Nanoclusters with GSH-Depleting Gold Nanoclusters for Enhanced Chemodynamic Therapy via Amplification of Oxidative Stress.

It is hoped that the developed PVP@Fe–Au can provide an efficient strategy for designing high-efficiency CDT agents via boosting ROS generation and suppressing the antioxidation system.

Wenying Mi, Mingkun Jin, Xiaoting Yang et al. · 0 citations
Open access Aug 2026

Cancer cell membrane-coated superparamagnetic iron oxide nanoparticles as a theranostic platform for magnetic hyperthermia and MR imaging.

Superparamagnetic iron oxide nanoparticles (SPIONs) have emerged as promising theranostic agents owing to their magnetic hyperthermia efficiency and capability as magnetic resonance imaging (MRI) contrast agents. However, achieving sufficient intracellular iron accumulation remains a critical challenge for effective th...

Yu-Chen Yuan, Satoshi Okada, Akira Sumiyoshi et al. · 0 citations
Aug 2026

Self-exploding tumor microenvironment-responsive nanomedicine as "ROS Bomb" ignites STING pathway for triple-negative breast cancer immunotherapy.

It is reported that horseradish peroxidase (HRP) can catalyze artemisinin to generate ROS, and a "ROS bomb" nanomedicine was designed for antitumor immunotherapy, offering a potent approach for treating deep-seated tumors.

Ke-Qiang Lu, Yaoquan Su, Xing-Chen Zhou et al. · 0 citations
Open access Aug 2026

Magnetic Hyperthermia via Zn0.2Mn0.8Fe2O4 Oleic Acid Nanoparticles Enhances Chemotherapy Efficacy in a Lewis Lung Carcinoma Model

Background/Objectives: Combining chemotherapy with local magnetic hyperthermia (MHT) is promising because heating tumor tissue can increase cell damage, sensitize cells to cytostatic drugs, impair DNA repair, and change tumor microenvironment permeability. This creates conditions for enhancing the antitumor efficacy of...

D. E. Yakobson, M. Zharkov, O. A. Kulikov et al. · 0 citations
Open access Aug 2026

Magnetic nanoflower-mediated hyperthermia activates concurrent apoptosis and ferroptosis on prostate PC3 and melanoma DX3 cells.

Magnetic hyperthermia therapy (MHT) has many potential applications in cancer therapy due to its controllable heating, precise targeting, and biocompatibility; however, its underlying mechanisms of damaging cancer cells are still not fully understood. Herein, we employed magnetic nanoflowers (NFs) as a high-performance...

Dongdong Guo, Xin-Yuan Hu, Samyog Adhikari et al. · 0 citations

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