Cerium molybdate-doped polyaniline nanoparticles are developed to enable a synergistic combination of photothermal therapy (PTT) and CDT, thereby triggering immunogenic cell death (ICD) and enhancing antitumor immunity and presenting a robust nanoplatform integrating chemodynamic and photothermal therapies for potent c...
It is hoped that the developed PVP@Fe–Au can provide an efficient strategy for designing high-efficiency CDT agents via boosting ROS generation and suppressing the antioxidation system.
Wenying Mi, Mingkun Jin, Xiaoting Yang et al.· Langmuir· 0 citations
Superparamagnetic iron oxide nanoparticles (SPIONs) have emerged as promising theranostic agents owing to their magnetic hyperthermia efficiency and capability as magnetic resonance imaging (MRI) contrast agents. However, achieving sufficient intracellular iron accumulation remains a critical challenge for effective th...
It is reported that horseradish peroxidase (HRP) can catalyze artemisinin to generate ROS, and a "ROS bomb" nanomedicine was designed for antitumor immunotherapy, offering a potent approach for treating deep-seated tumors.
Ke-Qiang Lu, Yaoquan Su, Xing-Chen Zhou et al.· Journal of Controlled Releas...· 0 citations
Background/Objectives: Combining chemotherapy with local magnetic hyperthermia (MHT) is promising because heating tumor tissue can increase cell damage, sensitize cells to cytostatic drugs, impair DNA repair, and change tumor microenvironment permeability. This creates conditions for enhancing the antitumor efficacy of...
D. E. Yakobson, M. Zharkov, O. A. Kulikov et al.· Pharmaceutics· 0 citations
Magnetic hyperthermia therapy (MHT) has many potential applications in cancer therapy due to its controllable heating, precise targeting, and biocompatibility; however, its underlying mechanisms of damaging cancer cells are still not fully understood. Herein, we employed magnetic nanoflowers (NFs) as a high-performance...