TL;DR
Environmental plasmid mediated HGT of multidrug resistant (MDR) Aeromonas spp.
It is shown that this engineered ‘probiotic plasmid’ prevents invasive AMR plasmids from entering bacterial populations in vitro and in vivo, in the mouse gut, and offers a promising new strategy to control invasive AMR plasmids and prevent AMR acquisition in high-risk settings, such as in hospitals or AMR-endemic regi...
Conjugation experiments demonstrated that the β-lactam resistance gene blaOXA-246 could be horizontally transferred from the donor MD9 strain to the recipient Escherichia coli 25DN strain, thereby potentially contributing to the dissemination of multidrug-resistant bacteria.
The study findings revealed that pELF-type plasmids utilize highly minimized conjugation machinery, which is similar to unusual systems previously identified in other gram-positive bacteria, such as Streptomyces.
Findings demonstrate strain-specific adaptive responses to aquatic environments and underline the context-dependent influence of plasmids in shaping adaptation.
Extended-spectrum β-lactamase genes in foodborne Salmonella enterica can disseminate through mobile multidrug-resistance platforms. IncHI2 plasmids are important resistance vehicles capable of carrying complex resistance regions and facilitating their horizontal transfer across diverse bacterial backgrounds, but the tr...
Background: The global spread of antimicrobial resistance in Escherichia coli (E. coli) from food-producing animals is a critical concern within the One Health framework, particularly because of the potential transmission of clinically relevant resistance determinants across the animal–environment–human interface. Alth...
We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.
