Vitamin D offers a protective role in neurodegeneration in healthy aging adults, the more likely mechanisms being enhanced neurogenesis, improved antioxidant status and modulation of neuronal calcium as hallmarks of reducing the levels of the amyloid marker Aβ42.
BACKGROUND
Studies have shown a relation between Vitamin B12 (B12) and cognitive impairment in Alzheimer's disease (AD). However, B12 levels do not indicate the severity of the disease. High homocysteine-induced neuroinflammation has been related to the pathogenesis of AD.
AIM
This study aimed to determine the correl...
Tanima Mandal, Uma Sinharoy, Koushik Biswas et al.· Annals of African medicine· 0 citations
Introduction: Vitamin D status has been investigated as a modifiable risk factor with cognitive decline. However, studies pertaining to this remain inconsistent across populations, and there are fewer studies associating vitamin D status, cognitive decline, amyloid markers and oxidative stress markers in older adults....
Rajalakshmi Ramashetty, Rimshia Naaz, R. M. et al.· Nutrients· 0 citations
Background Health-related factors may influence blood-based biomarkers (BBBM) of Alzheimer's disease (AD). In this analysis, associations between modifiable factors and plasma biomarkers of neurodegeneration were investigated across the Alzheimer's disease spectrum and in cognitively healthy controls in a cerebrospinal...
Carolin I. Kurz, Marleen Taute, Paulina Tegethoff et al.· Aging Brain· 0 citations
The inverse relationship between BDNF and S100 B suggests a link between neurotrophic and neuroinflammatory processes and nursing interventions that enhance BDNF may also affect S100 B level, which may foster brain health in older adults.
Ryuzo Orihashi, Takumi Shiraishi, Toru Murakawa-Hirachi et al.· Biological Research for Nurs...· 0 citations
OBJECTIVE
Behavioral and Psychological Symptoms of Dementia (BPSD) are highly prevalent in Alzheimer's disease (AD) and constitute a major therapeutic challenge. Although nutritional deficiencies are common among AD patients, their relationship with BPSD remains poorly understood. This cross-sectional study aimed to ex...
Wen-Jing Nie, Zhen-Tao Liang, Qing-Rong Fu et al.· Acta Psychologica· 0 citations
Introduction Dementia constitutes a major and rapidly growing public health challenge worldwide. The identification of its risk factors and potential contributors has therefore become a major focus of research. This study aimed to investigate the association between serum 25(OH)D concentration and cognitive performance...
Ganna Kravchenko, S. S. Stephenson, Julia Dmuchowska et al.· Frontiers in Nutrition· 0 citations
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