Aug 2026· Naunyn-Schmiedeberg's Archives of Pharmacology· 0 citations· 17 references
Medicine
TL;DR
In conclusion, remimazolam may represent a safe and effective alternative to midazolam for upper gastrointestinal endoscopy, with faster cognitive recovery, as reflected by shorter time to full alertness and earlier discharge.
BACKGROUND
Remimazolam is a novel ultra-short-acting intravenous benzodiazepine, while sevoflurane is a widely used inhalational anaesthetic for general anaesthesia (GA). Both agents are associated with risks of haemodynamic instability and postoperative nausea and vomiting (PONV), which can affect patient safety and r...
L. Takayama, Kevlin de Souza, David Abraham Batista da Hora et al.· European Journal of Anaesthe...· 0 citations
We compared ciprofol with propofol for painless gastrointestinal endoscopy, focusing on dose, recovery, induction, satisfaction, and adverse events.
PubMed and Embase were searched through May 2026 for randomized controlled trials in adults undergoing painless gastrointestinal endoscopy. We pooled weighted m...
Jing Liu, Jun Yu, Zhi-Yong Chen et al.· Frontiers in Pharmacology· 0 citations
Remimazolam significantly shortened recovery time and reduced flumazenil use in elderly patients, which may reduce staff workload after ERCP; larger studies are needed to establish comparative safety.
Suguru Ito, Y. Tanisaka, S. Ryozawa et al.· Scandinavian Journal of Gast...· 0 citations
Background: Procedural sedation in children remains a complex clinical challenge. Midazolam has served as the conventional standard, yet intranasal dexmedetomidine has emerged as an attractive alternative offering potential advantages regarding respiratory safety alongside improved behavioral recovery.
Objectives: To s...
Ahmad M.Alridahie, Saleh K.Almasoud, Ammar K.Alhajjaj et al.· Annals of Middle Eastern Med...· 0 citations
A range of pharmacologic options is available for acute migraine treatment, yet the efficacy and safety of commonly used over-the-counter (OTC) therapies relative to newer prescription agents remain unclear. Given the scarcity of direct head-to-head trials, this network meta-analysis (NMA) of randomized controlle...
A. Mitra, B. Franks, R. Petruschke et al.· Frontiers in Neurology· 0 citations
Background: For decades, chlorthalidone (CTD) was favoured over hydrochlorothiazide (HCTZ) based on its longer half-life and historical efficacy data. However, recent high-powered pragmatic trials and large-scale observational cohorts challenge this preference. We aimed to synthesise contemporary evidence comparing the...
L. Choonara, M. Vally· SA Heart· 0 citations
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