Cultivation-dependent effects of quorum sensing signals on a lactic acid and chain-elongating bacterium

Lena Depaz A. Nys Shanaya Scharloo Celia Alvarez Fernandez Jana De Bodt Josefien Van Landuyt J. de Vrieze Ramon Ganigué

Aug 2026 · bioRxiv · 0 citations · 43 references

Biology

TL;DR

It is demonstrated that responses to quorum sensing molecules are strongly dependent on the signal, substrate, microbial context, and cultivation conditions, highlighting the limited predictive power of pure-culture assays for microbial communication in interacting communities and emphasizing the importance of studying signal perception under process-relevant cultivation conditions.

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