TL;DR
The findings indicate that ITGA7 was the gene associated with breast cancer, which plays an important tumorigenic function and acts as a suppress gene in breast cancer.
Functional studies demonstrated that IFI35 knockdown effectively suppressed BRCA cell proliferation, migration, and invasion, while promoting apoptosis, and is a potential therapeutic target for BRCA.
Background Lysine acetyltransferase 7 (KAT7), also known as HBO1 or MYST2, is highly expressed in multiple cancers. This study aims to explore the expression patterns of KAT7 in breast cancer and its impact on phenotypes of breast cancer cells. Methods The expression of KAT7 and the overall survival of patients were an...
BACKGROUND Transmembrane protein 61 (TMEM61) has previously been reported in several malignancies. However, its function in ovarian cancer remains unclear. Here, we aimed to investigate the role and underlying mechanisms of TMEM61 in ovarian cancer cells. METHODS Differentially expressed genes were identified by anal...
miRNAs are small molecules which influence cellular function by regulating the expression of mRNA. They control various stages of the cell’s existence, including differentiation, proliferation and finally death. In cancer cells, miRNAs can become dysregulated, enabling the cell to escape growth suppression and resist...
Elevated MXRA5 expression exhibited a positive correlation with advanced lymph node metastasis and impaired clinical prognosis, and its potential as a valuable prognostic biomarker and therapeutic target for managing metastatic disease is revealed.
This study identifies ZUP1 as a potential oncogenic factor and a robust independent prognostic biomarker in breast cancer and suggests that ZUP1 is a novel multifaceted biomarker with significant implications for personalized treatment strategies in breast cancer.
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