AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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Findings identify VV7 as a stable DPP-IV inhibitory peptide from bitter leaf and provide structural insight into its enzyme-level interaction with DPP-IV.
Computational findings suggest that the tested compounds may serve as preliminary scaffolds for developing quorum-sensing inhibitors targeting LuxR; however, they do not constitute experimental evidence of antibacterial activity.
Pumpkin seed protein (PSP) is a promising precursor of bioactive peptides, but the mechanisms underlying the α-glucosidase inhibitory activity of its hydrolysates are not yet fully understood. In the present work, a previously unreported tetrapeptide with α-glucosidase inhibitory activity, YYPW, was obtained from PSP t...
Findings indicate that the tested compounds possess potential as antibacterial and quorum sensing inhibitory agents by targeting LuxR, however, further in vitro and in vivostudies are required to validate their biological activity and therapeutic potential.
This study employed a comprehensive approach integrating peptidomics, in silico analysis, and multispectroscopic techniques to screen novel α-glucosidase inhibitory peptides from mulberry leaf protein digests. The following α-glucosidase inhibitory peptides were selected from 141 identified peptides: GGLDFTK (IC50 = 0....
Food-derived bioactive peptides are promising alternatives to conventional xanthine oxidase (XO) inhibitors, yet individual XO inhibitory peptides from sesame protein remain uncharacterized. Here, sesame and peanut protein isolates were screened with four proteases; the trypsin hydrolyzate of sesame (TSH, 120 min) show...
Fractionation of the ethyl acetate extract of unripe Solanum torvum Swartz fruits led to the isolation of a new pregnane-type steroid, solacanin C (1), together with six known steroidal compounds. Their chemical structures were elucidated using comprehensive spectroscopic analyses, including 1D- and 2D-NMR, FTIR, HRESI...
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