TL;DR
Results show apigetrin not only improves the skin barrier of the epidermis but also exhibits excellent anti-inflammatory effects in a dermis cell model.
The active ingredient, Tetrandrine (TET), derived from the Nidus Vespae, exhibits diverse pharmacological activities, including anti—inflammatory, antioxidant, and immunomodulatory effects. To demonstrate the effectiveness of TET in the treatment of atopic dermatitis and its underlying mechanism of action. The atopic d...
This study highlights WSCE as a potential anti-dermatitis agent, suppressing pro-inflammatory mediators in T+I-stimulated keratinocytes via MAPK and NF-κB regulation and position WSCE as a promising candidate for ISD management.
Psoriasis is a chronic inflammatory skin disorder characterized by keratinocyte hyperproliferation, immune dysregulation, oxidative stress, and impaired epidermal barrier function. In the present study, we investigated the protective effects of Tempol, a membrane‐permeable nitroxide with antioxidant and anti‐inflammato...
UVB radiation induces epidermal damage and inflammatory responses through immune-mediated pathways in the skin. Cannabidiol (CBD), a non-psychoactive phytocannabinoid derived from Cannabis sativa, has demonstrated anti-inflammatory effects in various disease models; however, its therapeutic application in UVB-ind...
It is demonstrated that lut-7-O-rutin alleviates joint inflammation and synovial hyperplasia in RA may be mediated through inhibiting the PI3K/AKT/NF-κB signaling pathway and downregulating cell cycle-associated proteins, highlighting its potential as a therapeutic agent for RA.
Psoriasis is a chronic inflammatory skin disorder characterized by dysregulated cytokine signaling and keratinocyte hyperproliferation, in which extracellular vesicles, particularly exosomes, play key roles in mediating intercellular inflammatory communication. In this study, we evaluated the pharmacological effects of...
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