Statistical optimization of extracellular antimicrobial metabolite production by Streptomyces enissocaesilis ASB isolate targeting multidrug-resistant pathogens
Aug 2026· Biologia· Vol 81· 0 citations· 88 references
TL;DR
Findings highlight S. enissocaesilis ASB as a promising source of extracellular bioactive metabolites and provide a foundation for future studies involving compound purification, structural characterization, safety evaluation, and translational development against MDROs.
The integrated experimental and in silico approach highlights soil-derived actinomycetes as versatile and sustainable bioresources with significant pharmaceutical and biotechnological potential, emphasizing their role in combating antimicrobial resistance and enabling the rational development of novel therapeutic and i...
Meghana Arivilu, S. Sulthana, Vijay Ramesh et al.· Journal of Pure and Applied...· 0 citations
This study investigated the isolation, molecular characterisation, and antibacterial profiling of metabolite-producing lactic acid-related bacteria from traditionally fermented cow milk (nono) with significant antibacterial potential, which can serve as natural antimicrobial agents for food preservation and therapeutic...
Azeezat Funmilola Shittu, Abdulsalami Mohammed Sani, A. Haroun et al.· The Scientific World Journal· 0 citations
Abstract This study evaluated the antimicrobial and antibiofilm activities of metabolites produced by a Streptomyces strain isolated from impacted soil against Staphylococcus aureus. The study employed the Streptomyces sp. SLA3 strain. Secondary metabolites were obtained through submerged fermentation followed by liqui...
S. A. S. Gouveia, D. C. P. Santos, S. L. Pires et al.· Brazilian Journal of Biology· 0 citations
It is demonstrated that tropical peat swamp forest soils represent a valuable and underexplored reservoir of bioactive actinobacteria with promising antimicrobial potential and highlights the importance of peatland ecosystems as sources of novel microbial metabolites that may contribute to future pharmaceutical and bio...
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Background: The emergence of antimicrobial resistance is growing swiftly and this requires the discovery of new antibiotic-producing microorganisms. The species of Streptomyces are still a major source of clinically significant secondary metabolites, including rifampin, one of the bactericidal agents critical to the tr...
Ali Arkan Majhool, Ahmed A. Hadi Almuttairi, Abbas Abduladeem Abbas· Medical Journal of Ahl al-Ba...· 0 citations