Jul 2026· Frontiers in Digital Health· Vol 8· 1 citation· ⚡ 1 influential· 124 references
Medicine
TL;DR
AI can strengthen healthcare teams and advance value-based care, but scaling requires aligned incentives, rigorous evaluation standards, equity safeguards, and coordinated governance—echoing lessons from national EHR implementation.
Abstract
Background AI is being introduced into clinical workforces during a critical transition toward integrated, value-based models of care, where its greatest promise lies in augmenting clinician judgment and expanding the reach of already strained healthcare teams. Yet clinical adoption remains limited because most AI systems lack reimbursement pathways, impose substantial implementation costs, and lack standardized mechanisms for integration into electronic health records (EHRs). These gaps create misalignment between technological capability and clinical usability. This paper identifies financial, regulatory, and workflow structures required for AI to operate safely, predictably, and sustainably across key domains of healthcare. Methods This narrative synthesis reviews clinical, economic, regulatory, and implementation-science literature from 2022 to 2025. Four domains were analyzed: (1) AI augmentation of clinical workflows; (2) reimbursement structures and CPT coding pathways; (3) EHR-based AI deployment and governance; and (4) economic and equity considerations for large-scale implementation. Sources included peer-reviewed reviews, white papers, consensus statements, and health policy analyses. Results AI tools demonstrated benefits in diagnostic accuracy, decision support, and documentation efficiency, particularly in radiology, cardiology, and EHR-integrated workflows. Adoption was hindered by absent reimbursement for clinician-reviewed AI outputs. Implementation and monitoring costs fell heavily on health systems, risking widened disparities. Additional concerns included accuracy, bias, generalizability, and limited oversight. Enabling conditions included clinician-in-the-loop review, auditable outputs, equity-centered validation, and alignment with evolving payment models. Conclusions AI can strengthen healthcare teams and advance value-based care, but scaling requires aligned incentives, rigorous evaluation standards, equity safeguards, and coordinated governance—echoing lessons from national EHR implementation.
Artificial intelligence (AI)-enabled healthcare systems introduce clinical safety, operational and governance risks across development, deployment and postdeployment stages. Although multiple AI risk assessment frameworks exist, they are often cross-sector, lengthy and difficult to operationalise in ways that suppo...
Tahmina Zebin, Jin-Yang Wu, F. Colecchia et al.· BMJ Innovations· 0 citations
OBJECTIVE
To examine the characteristics, implementation strategies, and reported impacts of Human-in-the-Loop (HITL) processes across the lifecycle of AI-enabled Clinical Decision Support Systems (CDSS), and to propose a reporting checklist for HITL in clinical AI research.
INTRODUCTION
HITL is a conceptual and tech...
Michael Bakker, Aaron Van Garderen, Tamara L. Paget et al.· International Journal of Med...· 0 citations
This study introduces a comprehensive value framework tailored to artificial intelligence in healthcare, extending evaluation beyond narrow cost–outcome ratios and provides researchers with clear dimensions for developing indicators and evaluation tools for responsible AI use in health services.
An AI Productivity Index is proposed to complement existing safety, efficacy and economic assessments by evaluating operational impact, implementation burden, opportunity costs and post-deployment consequences.
Y. Al-Ajlouni, Basile Njei· Clinical medicine (London)· 0 citations
Clinical AI has advanced rapidly for bounded in-visit tasks such as prediction, documentation, and message generation, yet many costly failures in care occur outside the encounter when follow-up, handoffs, and communication break down. We argue that the next challenge for clinical AI is not only better task performance...
Saif S. Khairat, C. Safran· npj Health Systems· 0 citations
The integration of artificial intelligence into healthcare has accelerated dramatically, with the FDA authorizing 1,430 AI/ML-enabled medical devices by the end of 2025 including 331 authorizations in that year alone yet the evidentiary foundation for many deployed tools remains limited, and accountability frameworks h...
Tony T. Williams, Amna Jatoi, Sazain Malik et al.· Journal of Global Social Tra...· 0 citations
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