This review summarizes existing and emerging therapeutic strategies for CKD-associated anemia, with particular emphasis on HIF-PH inhibitors and their clinical potential and risks.
This review summarizes existing and emerging therapeutic strategies for CKD-associated anemia, with particular emphasis on HIF-PH inhibitors and their clinical potential and risks.
Current evidence regarding the efficacy, safety and clinical applications of emerging therapies for anemia in CKD are summarized and future perspectives in personalized renal anemia management are discussed.
A. K. M. Shahidur Rahman, M. Karim· Haematology Journal of Bangl...· 0 citations
This review summarizes the recent advances in the pharmacological management of CKD-associated anemia, focusing on iron supplementation, ESAs, and HIF-PHIs.
Takahiro Saito, M. Nangaku, I. Mimura· Expert Opinion on Pharmacoth...· 0 citations
Anemia is a common complication of chronic kidney disease (CKD) and is associated with CKD progression and other adverse outcomes, which can result in increased rates of cardiovascular events and mortality. The search for the most effective and at the same time safe therapy for anemia in patients with CKD has always be...
Mario Bonomini, L. Del Vecchio, R. Minutolo et al.· Journal of Clinical Medicine· 0 citations
Anemia is one of the most common complications affecting individuals with chronic kidney disease (CKD). It is driven primarily by relative erythropoietin (EPO) deficiency, chronic inflammation, and altered iron metabolism. Emerging therapies, known as hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs), o...
Joel Shah, W. Wells-Gatnik, Kunal Sharma et al.· Clinical Nephrology· 0 citations
Objective: Chronic kidney disease (CKD)-associated anemia is substantially driven by chronic inflammation, which promotes hepcidin upregulation, restricts iron availability, and impairs erythropoiesis. Conventional therapies, including erythropoiesis-stimulating agents and iron supplementation, primarily address erythr...
Harsh J. Shah, Jacky K. Pariyani, Kalyani V. Shinde et al.· Turkish Journal of Internal...· 0 citations
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