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Rotational asymmetry is required to position centrioles at the base of the primary cilium

Meriem Boumendjel Griselda Wentzinger Mohamed Bahida Tamara Advedissian Tania Joanet Futura Gattobigio F. Begum Nicolas Moisan M. van Breugel T. Ochi Juliette Azimzadeh
Jul 2026 · bioRxiv · 0 citations
Biology

TL;DR

The results establish that rotational asymmetry relies on the coordinated recruitment of asymmetric landmarks along centrioles and is necessary for positioning the centrioles in a configuration that is widely conserved in ciliated cells.

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