Aug 2026· Influenza and Other Respiratory Viruses· Vol 20· 0 citations· 12 references
Medicine
TL;DR
A retrospective analysis to detect EV‐D68 in archived samples collected from hospitalized children with SARI in Zambia from 2018 to 2020 identified eight positive samples in 2020, and genetic sequence analysis showed that all sequences belonged to subclade A2.
Abstract
Enterovirus D68 (EV‐D68) is a cause of severe acute respiratory infections (SARI) and is associated with acute flaccid paralysis. However, data on EV‐D68 in Africa, where SARI remains a leading cause of morbidity and mortality among children, remain limited. We conducted a retrospective analysis to detect EV‐D68 in archived samples collected from hospitalized children with SARI in Zambia from 2018 to 2020. We identified eight positive samples in 2020, and genetic sequence analysis showed that all sequences belonged to subclade A2. Continuous monitoring is crucial to enhance understanding of the epidemiology and molecular characteristics of EV‐D68 in Africa.
Enterovirus D68 (EV-D68) primarily causes respiratory illness in children but is also associated with serious neurological outcomes. Although EV-D68 circulation has historically demonstrated a biennial pattern, with peaks during summer and fall, infections can occur year-round, with unpredictable outbreaks. Notab...
Haya Hayek, J. Amarin, Olla Hamdan et al.· Journal of the Pediatric Inf...· 0 citations
BACKGROUND
Enterovirus D68 (EV-D68) causes cyclical outbreaks worldwide. Though EV-D68 can rarely cause acute flaccid myelitis, it commonly causes respiratory disease. In particular, EV-D68 causes outbreaks of severe asthma-like respiratory disease, but few systems have the capability to detect EV-D68 cases.
METHODS...
Hai Nguyen-Tran, Molly Butler, Dennis Simmons et al.· The Pediatric Infectious Dis...· 0 citations
It is revealed EV-D68 circulated endemically in this pediatric population, establishing a high population immune baseline (>90.0%) with distinct age-dependent patterns and providing key reference data for ongoing serosurveillance, outbreak risk assessment, and the evaluation of future vaccines or immunoprophylactic str...
Li-Ting Wang, Qi-Guo Zhu, Yi Lu et al.· Viruses· 0 citations
ABSTRACT Enteroviruses (EVs), which include numerous types, are among the most common pathogens causing infections in children. EVs can cause diverse diseases, including herpangina, hand‐foot‐and‐mouth disease, myocarditis, pneumonia, meningitis, encephalitis, and acute flaccid paralysis. Severe cases may result in ped...
Xiang-Peng Chen, Ling-Yun Guo, X. Lei et al.· Pediatric Investigation· 0 citations
Objective Norovirus (NoV) is a major pathogen causing acute gastroenteritis (AGE) worldwide, imposing a substantial disease burden. This study aimed to investigate the epidemiological, clinical and genotypic characteristics of NoV infection in pediatric patients with AGE in Ezhou, central China. Methods Between January...
Dan Luo, Siyue Tang, Yingru Liu et al.· Frontiers in Physiology· 0 citations
Current evidence on the epidemiology, clinical presentation, diagnostic challenges, and prevention of selected arboviral infections in children within the European context are summarized, highlighting persistent gaps in pediatric-specific data and implications for preparedness and public health.
G. Sturniolo, Silvia Garattini, Denis Doni et al.· Viruses· 0 citations
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