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Sep 2026

Central residue chirality directs molecular packing and self-assembly of Val-Val-Ile tripeptides.

Short peptides are versatile building blocks for self-assembled biomaterials due to their biocompatibility, biodegradability, and ease of preparation. Most studies of short-peptide self-assembly involve aromatic residues such as phenylalanine or peptides containing terminal capping groups, where π-π interactions play a...

Munkhdalai Chagdarjav, Yuki Yoinara, Hisako Sato et al. · 0 citations
Sep 2026

Unnatural amino acids program thermoresponsive protein-polymer diblocks into shape-shifting nanostructures.

Control over the morphology and function of self-assembling polymers remains a central challenge in engineering adaptive biomaterials and synthetic biological systems. Here, we establish that recombinant elastin-like polypeptide-resilin-like polypeptide diblocks can be programmed through incorporation of unnatural amin...

Daniela S. Strugach, Y. Pasternak, Oren Tiv et al. · 0 citations
Sep 2026

Multifunctional Hydrogel Based on Synergistic Hydrophobic and Multivalent Hydrogen-Bond Interactions

Developing soft materials that integrate high mechanical performance, self-healing, adhesion, and stimulus-responsive functions remains challenging due to the trade-off between dynamic reversibility and mechanical resilience. Here, we report a P(AA-MA-OA-FHMA) hydrogel fabricated via one-pot free-radical copolymeriza...

Zeng-Hua Zhu, Shan-Shan Liao, He Zhang et al. · 0 citations
Sep 2026

Histidine-substituted β-sheet peptide networks with tunable viscoelasticity and pH-modulated transport.

Three short β-sheet-forming peptides with graded histidine substitution were designed as minimal supramolecular networks to systematically examine how sequence-level variation regulates supramolecular organization, viscoelastic response, and pH-modulated molecular transport in aqueous environments.

Wen-Bo Jia, Xinyue Yang, Li-Bo Yuan et al. · 0 citations
Review Sep 2026

Recent Advances in Organic Supramolecular Gels: Self-Assembly and Functional Applications.

Organic supramolecular gels formed through the self-assembly of π-conjugated molecules such as azobenzenes, coumarins, perylenes, and pyrenes have emerged as versatile materials with diverse functional applications. These gels rely on noncovalent interactions, including hydrogen bonding and π-π stacking, enabling tunab...

Mani Rajasekar · 0 citations
Open access Aug 2026

Engineering the interface: pH-dependent self-assembly of lysine-tyrosine synthetic copolypeptides for anti-biofilm implant coatings.

Developing resilient antimicrobial coatings for medical implants requires a sophisticated balance between direct bactericidal activity and resistance to bacterial adhesion. While poly(L-lysine) provides effective membrane disruption, its performance is often compromised by the accumulation of cellular debris, which fac...

Juhi Singh, Hunter B. Wood, Dharika Srikanth et al. · 0 citations

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