Aug 2026· Interdisciplinary Sciences Computational Life Sciences· 0 citations· 29 references
Medicine
TL;DR
DynMedRec captures fine-grained drug information by modeling the interactions between substructures and employing a clinical-context query mechanism to generate adaptive molecular representations, and integrates structural correlations among medical codes to enhance visit-level patient representations.
Experimental results demonstrate that MoTRANet outperforms existing mainstream baseline methods in terms of Jaccard, F1, and PRAUC, while achieving a relatively low DDI rate, validating the model's accuracy and safety.
Peng-Tao Jia, Jun-Hao Gao, Jing-Tao Sha et al.· IEEE transactions on computa...· 0 citations
Medication recommendation plays a critical role in clinical decision-making by supporting personalized and safe treatment planning. Existing methods rely heavily on historical co-occurrence patterns and primarily optimize discrete prescription prediction objectives, limiting generalization in rare or emerging disease s...
Jin-Ke Feng, Wenjie Du· Proceedings of the Thirty-Fi...· 0 citations
Medication recommendation aims to provide accurate and safe medication combinations tailored to patients’ clinical records. Existing methods suffer from two key limitations: insufficient modeling of disease–medication relationships, resulting in under-expressive medical entity embeddings, and limited capability in capt...
Qing-Chuan Xu, K. Che, Jia-Feng Li et al.· IEEE Access· 0 citations
The NexusOpti model, incorporating the Enhanced Gated Recurrent Unit (E-GRU) layer, outperforms the existing GRU model in terms of NDCG and Hit Ratio metrics and highlights the effectiveness of the model in advancing personalised, safer, and data-driven medication prescriptions.
Harichandra Khalingarajah, A. Vasudevan, P. Abinaya et al.· Scientific Reports· 0 citations