Vitamin D₃ in cancer prevention and therapy: molecular mechanisms, clinical evidence, and future perspectives

EXPRESS: Vitamin D and cancer connection: Is it a promise for cancer Prevention?

Traditionally, vitamin D has been recognized primarily for its role in regulating calcium homeostasis and supporting skeletal integrity. Current research has found growing evidences of other biological processes involving vitamin D that contribute to cancer etiology and pathogenesis. Recently, increasing scientific att...

VITAMIN D3 AND CANCER PREVENTION: FROM BIOLOGICAL MECHANISM TO CLINICAL EVIDENCE

Vitamin D3 (cholecalciferol) is a steroid prohormone synthesized in the skin as a result of UV-B light exposure or by dietary intake. In addition to the already proven action on calcium phosphate metabolism and bone physiology, there is an increasing body of research showing that vitamin D3 may impact carcinogenesis an...

The interplay between vitamin D3 and Nrf2 signaling: mechanistic insights and therapeutic potentials.

Dose-Dependent Effects, Metabolic Paradoxes, and Nutritional Implications of Flavonoids and Cancer.

Curcumin in ovarian cancer: mechanistic insights and translational potential

Phytochemicals as Multitarget Therapeutics in Pancreatic Cancer: Mechanisms, Clinical Evidence, and Translational Challenges

This review demonstrates the therapeutic potential of phytochemicals as multitarget agents in pancreatic cancer, emphasizing their molecular mechanisms, pharmacological properties, and translational relevance.