Perioperative intravenous lidocaine for gastrointestinal recovery and pain control in elective colorectal surgery: a systematic review and updated meta-analysis of randomized controlled trials

Efficacy and safety of intraperitoneal lidocaine in patients undergoing laparoscopic cholecystectomy: a systematic review and meta-analysis of randomized clinical trials.

Procedure-specific effects of intravenous lidocaine in adult spine surgery: a systematic review and meta-analysis of randomized controlled trials.

BACKGROUND AND OBJECTIVES Perioperative intravenous lidocaine infusion has been proposed as an opioid-sparing analgesic adjunct in spine surgery, but previous meta-analyses pooled heterogeneous procedures and may have obscured procedure-specific treatment effects. We evaluated the analgesic and opioid-sparing effects o...

Efficacy and safety of laparoscopic-guided transversus abdominis plane block versus port-site local anesthetic infiltration in laparoscopic cholecystectomy

Background: Postoperative pain following laparoscopic cholecystectomy remains a major clinical concern, and the optimal method of local anesthetic delivery is unresolved. This systematic review and meta-analysis evaluated the efficacy and safety of laparoscopic-guided transversus abdominis plane (LTAP) block versus por...

Current evidence of multimodal anesthesia on postoperative outcomes: A systematic review and Meta-analysis.

MMA shows no clear effect on postoperative pain at 24 h but reduces PONV incidence and opioid consumption, and larger, standardized trials are needed to define optimal MMA regimens and patient selection.

Effect of Intravenous Magnesium on Postoperative Pain and Analgesic Outcomes in Patients Undergoing General Anesthesia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Background: Intravenous magnesium sulfate has been proposed as an adjuvant analgesic in perioperative care; however, its effects on postoperative pain and related analgesic outcomes remain uncertain. Methods: A systematic search of the literature was conducted from 1 January 2015 through 19 January 2026 to identify ran...

Intravenous magnesium sulfate for analgesia in spinal surgery: a systematic review and meta-analysis of randomized controlled trials.

STUDY OBJECTIVE To evaluate the effects of perioperative intravenous magnesium sulfate on postoperative pain, opioid consumption, recovery, and adverse events in patients undergoing spinal surgery. DESIGN Systematic review with meta-analysis. SETTING Perioperative setting. PATIENTS Twenty-one randomized controlle...