TL;DR
It is suggested that flavonoid-based adjunctive interventions may represent a promising strategy for reducing chemotherapy-associated renal injury and warrant further mechanistic and translational investigation.
Background: Cisplatin is an effective and commonly used anticancer drug, but its therapeutic application is constrained by its potential to cause kidney injury. This experimental study investigated nebivolol protective effects, which is a third-generation selective β1-adrenoceptor blocker with additional β3-adrenocepto...
Background: Colistin is increasingly being used as a last-line treatment option for multidrug-resistant Gram-negative infections; however, its clinical use remains limited due to its nephrotoxic side effects. This study investigated the potential nephroprotective effects of ethyl pyruvate (EP) and rutin hydrate (RH), a...
The results substantiate the ethnomedical usage of Z. armatum bark extract by providing strong evidence that it functions as a powerful scavenger of free radicals and counteracts the harmful effects of CS in both histological and biochemical parameters.
This study investigated the protective effect of Chrysin, a naturally occurring flavone, against potassium dichromate (K₂Cr₂O₇)-induced nephrotoxicity in male Wistar rats. Thirty-two adult rats were allocated to four groups (n = 8 per group): control, potassium dichromate (7.5 mg/kg/day), potassium dichromate + Chrysin...
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