MIR4435-2HG overexpression facilitates the malignant progression of GBM through the miR-181d-5p/MALT1/NF-κB pathway and upregulates MALT1 expression and activates the NF-κB signaling pathway by sponging miR-181d-5p.
It is indicated that SLC12A9-AS1 is abnormally overexpressed in CRC cells and that its knockdown attenuates malignant phenotypes, at least in part through regulation of miR-139-3p.
Shiyu Zhao, Shuai Zhang, Qiong-Feng Tan et al.· Journal of Visualized Experi...· 0 citations
BACKGROUND
Cancer susceptibility candidate 9 (CASC9) has been implicated in several cancers through interactions with miR-590-3p, a microRNA with context-dependent oncogenic or tumor-suppressive functions. Dysregulation of this regulatory network may influence NF-κB signaling, a major pathway involved in tumor cell sur...
Samia Hussein, Mansour H. Zahra, Amr A. Shalaby et al.· Cancer Treatment and Researc...· 0 citations
It is suggested that lnc-DNAJC3-AS1 promotes GC progression, at least in part, through the miR-576-5p/LYPLA1 pathway, providing a potential target for GC treatment.
Zhen-Ni Sun, Ya-Sai Yao, Zhi-Jian Xu et al.· American Journal of Cancer R...· 0 citations
Prostate cancer (PCa) is a widespread malignancy with poor prognosis in advanced stages. However, the role of long non-coding RNA (lncRNA) HNF1A-AS1 in PCa progression and its underlying mechanisms remain largely unclear. This study aims to explore the expression trends and clinical associations of HNF1A-AS1 in PCa, an...
Epithelial ovarian cancer (EOC) is a highly lethal malignant tumor, with a poor clinical prognosis due to its early peritoneal metastasis. However, the molecular mechanism driving this malignant spread has not been elucidated. In this study, by aggregating the post-transcriptional regulatory network mediated by long no...
Wen-Xiao Li, Xiao-Li Ma, Zhi-Hui Li et al.· Discover Oncology· 0 citations
Gliomas, the most prevalent primary malignant brain tumors, are characterized by highly invasive growth patterns. Emerging evidence indicates that long non-coding RNAs are essential for regulating key oncogenic pathways. This study focuses on lncRNA LAMTOR5 antisense RNA AS1 (LAMTOR5-AS1, also known as SLC16A4-AS1), se...
Jia-Yi Li, Jing Li, Lin Yu· Neoplasma (Bratislava)· 0 citations
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