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Case report

[Utility of global coagulation assays for hemostasis management in hyperclearance-type autoimmune acquired coagulation factor V deficiency].

Haru Nakazawa Kazuto Togitani Mayuko Kitaoka Mitsuo Okada Yuki Kawasaki K. Ogiwara Masahiro Ieko A. Ichinose Teruto Hashiguchi Yoshiki Uemura
2026 · [Rinsho ketsueki] The Japanese journal of clinical hematology · Vol 67 8, pp. 902-909 · 0 citations
Medicine

TL;DR

This case underscores that, even in FV deficiency with a negative inhibitor screen, testing for anti-FV IgG is essential for identifying hyperclearance-type autoimmune FV deficiency (AiFVD), and ex vivo VET and TGT provided actionable assessments of hemostatic capacity and proved useful for guiding management in AiFVD.

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