TL;DR
Key aspects of phage biology that underpin the effective use of phages for therapy are explored, and clinical strategies for applying phages against a range of infections are outlined, highlighting their advantages and limitations.
The growing global threat of antibiotic resistance has necessitated research into alternative or complementary treatment methods. This study aims to demonstrate the current potential of bacteriophages (phages) in both clinical and industrial applications and to evaluate examples of their applications. Within the scope...
The rapid emergence of antimicrobial resistance poses a serious challenge to both human and veterinary medicine highlighting the urgent need to develop alternative antimicrobial strategies. Phage therapy has regained attention as a promising approach. However, its application in veterinary practice remains relatively l...
INTRODUCTION. Generalized infections and rising antimicrobial resistance necessitate the search for alternative therapeutic strategies, one of which is phage therapy. However, two fundamentally different models of its use for sepsis and bacteremia have emerged globally. A critical comparison of these models will hel...
PURPOSE OF REVIEW Bacteriophage therapy is a promising treatment on the horizon for multidrug resistant (MDR) and difficult-to-treat infections. RECENT FINDINGS There have been a number of case reports and case series using bacteriophages to treat MDR infections. This has sparked interest by many patients and provide...
ABSTRACT Since the discovery of bacteriophages over a century ago, bacteriophages have evolved from fundamental biological models into promising therapeutic agents, especially in the era of antimicrobial resistance and in the treatment of human diseases. This article systematically reviews the key milestones in phage r...
Introduction . In recent years, much attention has been paid to the development of antibacterial agents based on viruses of bacteria – bacteriophages. The effectiveness of such preparations was demonstrated in the treatment of a wide range of diseases caused by bacterial pathogens. However, the wide introduction of...
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