Aug 2026· Archives of Virology· Vol 171· 0 citations· 41 references
Medicine
TL;DR
This study characterizes Dp49, a newly discovered bacteriophage-derived depolymerase exhibiting potent enzymatic activity against bacterial exopolysaccharides and anti-biofilm activity, which demonstrates therapeutic potential by enhancing serum-mediated bactericidal activity and anti-biofilm activity.
Carbapenem-resistant
Acinetobacter baumannii
(CRAB) has become a predominant nosocomial pathogen worldwide, with biofilm formation and quorum sensing (QS) primarily responsible for its high antimicrobial tolerance and clinical refractory infections. Targeting bacterial virulence rather than conventional bacteri...
Bin Liu, Cai-Hua Li, Yi-Zhen Zhu et al.· Frontiers in Microbiology· 0 citations
It is suggested that vB_Kp_H122 may have potential as an antibacterial candidate against K57 MDR‐hvKP isolates, a novel lytic phage that specifically targets K57 capsular‐type MDR‐hvKP.
Cuilong Fan, Qiu Xu, S. Schwarz et al.· Transboundary and Emerging D...· 0 citations
Background Acinetobacter non-baumannii (Anb) species are reported worldwide to cause infections in both adults and neonates, although less frequently than Acinetobacter baumannii. However, limited information is available on their genomic diversity, resistance mechanisms, and virulence potential. This study investigate...
Subhasree Roy, Daichi Morita, Tanusree Das et al.· Frontiers in Microbiology· 0 citations
Introduction Carbapenem-resistant Acinetobacter baumannii (CRAB) poses a global health threat due to limited therapeutic options. Cefiderocol, a novel siderophore-conjugated cephalosporin, demonstrates potent in vitro activity against a variety of Gram-negative bacteria, including CRAB. However, cefiderocol's recent in...
Xiao-Chen Liu, Qing-Ye Xu, Jin-Tao He et al.· Frontiers in Microbiology· 0 citations
Acinetobacter baumannii presents a severe clinical challenge in critical care due to its rapid acquisition of drug resistance and its ability to form dense biofilms on medical equipment. While traditional antibiotic research focuses almost exclusively on essential bacterial viability targets, targeting virulence factor...
N. S. Faris, Omar Hadieh, Mohammad M. Hadieh· International Journal of Hea...· 0 citations
Background
The increasing prevalence of antimicrobial resistance (AMR) has created an urgent need for alternative therapeutic strategies. Acinetobacter baumannii, a major cause of hospital-acquired infections, has been classified by the World Health Organization as a critical priority pathogen due to its high levels of...
Souradeep Chowdhury, N. Rathor, M. Soneja et al.· Le infezioni in medicina· 0 citations
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