TL;DR
It is suggested that hsa_circ_0136682 drives breast cancer progression via the NCL/c-Myc axis.
As an oncogenic circRNA, hsa_circ_0001839 is critically implicated in gastric cancer progression and unfavorable patient outcomes, underscoring its dual application as a promising prognostic biomarker and a potential therapeutic intervention target.
BACKGROUND Circular RNA (circRNA) has been recognized as critical regulator in cancer progression. However, the mechanisms of circ_0081069 in breast cancer (BC) remain understood. The study was designed to elucidate the pathological significance and mechanism of circ_0081069 in BC. MATERIAL AND METHODS The expression...
The long noncoding RNA H19 has been widely attested as a promoter of breast cancer by favoring proliferation, migration, invasion, and tumor growth. In this study, we attempted to decipher molecular mechanisms underlying oncogenic activities of H19. Transcriptomic analyses revealed that H19 overexpression correlates wi...
Circular RNAs (circRNAs) exhibit wide expression across human tissues and play pivotal roles in tumorigenesis and cancer progression. However, studies regarding the function and mechanism of circRNAs in lung adenocarcinoma (LUAD) are insufficient, it needs to be further explored. This investigation aimes to describe dy...
It is suggested that UPK1A-AS1 is a hypoxia‐inducible oncogenic lncRNA that plays dual roles in cancer, with cancer type‐dependent associations with progression and immune modulation across malignancies and mechanistically mediating hypoxia‐associated drug resistance in HCC.
BACKGROUND Circular RNAs (circRNAs) are critical regulators of tumor biology. However, the role of circENO1 in gastric cancer (GC) remains unclear. This study investigated the biological function and molecular mechanism of circENO1 in GC. METHODS CircENO1 expression was evaluated using a publicly available dataset, c...
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