A copper-based MOF as both electrochemiluminescence emitter and dual coreactant accelerator for ultrasensitive immunosensing of Cyfra 21 − 1 via quenching by polydopamine

A Sm-MOF@Ag electrochemiluminescence immunosensor mediated by CuBi2O4@PDA dual-mode quenching for sensitive detection of anti-Müllerian hormone

A dual-quenching electrochemiluminescence immunosensor based on ABEI@Fe3O4@PDA-PdPt and Cu2−xS nanoflowers for sensitive detection of galectin-3

This work presents a novel strategy for the highly sensitive detection of Gal-3, leveraging the synergistic dual-quenching mechanism to achieve excellent analytical performance, thereby holding significant promise for clinical diagnostics and early disease monitoring applications.

Au@NiMnO3@g-C3N4-based electrochemiluminescence immunosensor for sensitive procalcitonin assay via quenching by tungsten-based polyoxometalate nanoclusters.

Intramolecular resonance energy transfer-driven self-enhanced p-COFs-based electrochemiluminescence sensor for the detection of CYFRA21-1.

Cytokeratin 19 fragment (CYFRA21-1) is a clinically significant tumor biomarker, and its ultrasensitive detection is of great importance for early diagnosis. Herein, we report a dual resonance energy transfer (RET)-regulated electrochemiluminescence (ECL) immunosensor enabled by a self-enhanced luminophore. Porphyrin-b...

Self-Enhanced Luminophore with an Intrinsically Integrated "Energy Ladder" and CdIn2S4-Enabled Coreactant Activation for Electrochemiluminescence Sensing.

In recent years, electrochemiluminescence (ECL) has attracted widespread attention in bioanalysis and clinical diagnostics. However, improving its luminescence efficiency remains a key challenge. In this work, an efficient ECL system was constructed by synergistically regulating the energy utilization of the luminophor...

Dual-Functional Nanoconfined Metal-Organic Frameworks with Aggregation-Induced Electrochemiluminescence Coupled with DNAzyme Motor for Ultrasensitive miRNA-21 Biosensing.

This work provides a paradigm integrating supramolecular engineering with DNA nanotechnology, which paves the way for sensitive biodetection and preliminary clinical screening.