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Sep 2026
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This report focused on synthesizing a biodegradable material based on poly(β-amino ester) hydrogel with curcumin loaded for application as a wound dressing treatment, as well as examining other physicochemical and physiological properties. The hydrogel was prepared via aza-Michael addition between cystamine and poly(et...
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· RSC Advances · 0 citations
Open access
Aug 2026
Fabrication and characterization of calcium phosphate-reinforced alginate/gelatin composite hydrogels with pH-dependent ciprofloxacin release behavior
The results suggest that the prepared hydrogel system could be used for a gradual, pH-dependent drug delivery.
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Open access
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Engineering functional halloysite nanotubes via dual-biopolymer interfacial assembly for pH-responsive antibiotic delivery
Localized, pH-responsive drug delivery systems offer an effective strategy to enhance antibiotic efficacy and overcome the limitations of conventional systematic therapies for chronic infected wounds. In this study, functional halloysite–chitosan–xanthan gum (HNT–CS–XG) nanocomposites were engineered for the contro...
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Functional alginate-chitosan packaging nanofilms enhanced with calcium chloride and in situ synthesized ZnO@MgO nano-heterostructures
The use of biodegradable materials in food packaging has gained increasing attention as a sustainable alternative to conventional plastics. In this study, calcium chloride-loaded nanofilms were developed using sodium alginate (NaAlg) as the primary polymer matrix, with chitosan (Ch) added at varying concentrations, res...
S. Selim, S. Al-Mijalli, A. Hashem et al.
· RSC Advances · 0 citations
Sep 2026
Systematic rheological investigation of chitosan-modified magnetite-reinforced thermosensitive Pluronic F127/chitosan hybrid hydrogels.
Polymer-modified magnetite nanoparticles hold great promise for diverse biomedical applications, including drug delivery, magnetic hyperthermia, and tissue engineering. However, ensuring their long-term functionality and stability for in vivo applications remains a significant challenge. In this work, chitosan-modified...
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Open access
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Hydrogel crosslinking mechanisms influence the release and functional delivery of lipid nanoparticles
Investigating the release, stability, cellular uptake, and transfection capability of LNPs released from four hydrogel systems representing distinct crosslinking mechanisms shows that hydrogel composition is a critical determinant of mRNA-LNP release, stability, and functional delivery.
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