Towards Sustainable Bioanalysis: First Green-Validated Synchronous Fluorimetric Platform for Nano-Level Determination of Co-Administered Empagliflozin and Favipiravir across Various Matrices
Jul 2026· Journal of Analysis and Testing· Vol 10, pp. 1043 - 1052· 0 citations· 41 references
TL;DR
An ultrasensitive and environmentally sustainable fluorimetric technique for the concurrent estimation of EGF and FPV in various matrices (pharmaceuticals and spiked biological fluids) could empower clinicians with more comprehensive analytical data on drug concentrations and potential drug interactions, facilitating more informed decision-making in the therapeutic management of diabetic patients with COVID-19.
A green synchronous spectrofluorimetric method was developed to overcome this limitation by improving spectral resolution through synchronous scanning of the excitation and emission monochromators, and demonstrated satisfactory accuracy, precision, selectivity, and reproducible analytical performance.
A. Alrashidi, Galal Magdy, A. Radwan· RSC Advances· 0 citations
The recent clinical introduction of the piroxicam (PIR) and venlafaxine hydrochloride (VEN) combination has highlighted the need for analytical methodologies capable of simultaneously quantifying both drugs while minimizing the environmental burden of routine pharmaceutical analysis. To date, only a chromatographic met...
B. Alsfouk, Lateefa A. Al-Khatee, Omkulthom M. Al Kamaly et al.· BMC Chemistry· 0 citations
Gefitinib is an epidermal growth factor receptor inhibitor used in non-small-cell lung cancer. This study developed a micelle-enhanced spectrofluorimetric method for its determination in tablets using native fluorescence and Cremophor RH 40 without derivatization. Experimental conditions were screened by a univariate a...
A. Bakheit, Abdullah M. A. Alzaid, Abdulrahman A. Almajed· International Journal of Mol...· 0 citations
This study aimed to develop and validate a sensitive, environmentally friendly analytical method for the simultaneous quantification of donepezil and rivastigmine in human plasma to support therapeutic drug monitoring (TDM). The approach combined a novel dispersive solid-phase extraction (dSPE) utilizing a purposely sy...
M. Vardast, Haniye Ranjkeshzadeh· Turkish journal of analytica...· 0 citations
Greenness assessment using AGREE, BAGI, and Eco-scale metrics confirmed the method as a highly sustainable and cost-effective alternative for routine pharmaceutical quality control and bioanalytical applications.
Muhammad Naeem Khan, Irfan Shah, Shahzad Hameed et al.· Chemistry Africa· 0 citations
Early diagnosis of ovarian cancer remains a major clinical challenge. Human epididymis protein 4 (HE4) has emerged as a promising biomarker for early OC detection. To address limitations of existing HE4 quantification methods, we developed a nano-optical biosensor based on a luminescent europium-thiosemicarbazide (Eu-T...
Ahmed Wanas, Ameera S. Alshinnawy, Moshira M. Abdel Waled et al.· Spectrochimica Acta Part A -...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
