Advancing in Personalization of Psychological, Indicated Preventive Interventions: A Randomized Controlled Trial in Adolescents at High-Risk of Developing Emotional Disorders.
Jul 2026· Child Psychiatry and Human Development· 1 citation· 86 references
Medicine
Abstract
This randomized controlled trial evaluated the effectiveness of a personalized, transdiagnostic, indicated preventive intervention (PROCARE-I+) compared to its standard format (PROCARE-I) in high-risk adolescents. One hundred and thirty-nine participants were randomized to either a standard transdiagnostic, indicated preventive intervention (PROCARE-I; n = 70) or the personalized intervention with add-on modules (PROCARE-I+; n = 69). Participants were assessed at post-intervention at 6 and 7-month follow-ups (the latter, one month after receiving a booster session). Results showed significant reductions not only in anxiety and depressive symptoms, but also in emotional risk. Improvements in emotion regulation, psychological flexibility, resilience, and quality of life were also found. While both interventions were effective, the personalized PROCARE-I+ intervention revealed greater improvements over time in key outcomes. These findings suggest the potential added value of personalization in transdiagnostic, indicated prevention and its potential to enhance long-term outcomes in adolescents at high risk of developing emotional disorders.
One of the main challenges in clinical psychotherapy is disseminating effective psychological treatments to the millions who need them but lack access. Transdiagnostic interventions, particularly those delivered online, can help bridge this treatment gap. However, these interventions, often provided as a “one-size-fits...
Fernanda Longo Elia, A. García-Palacios, Cristina Botella et al.· Frontiers in Psychiatry· 0 citations
Abstract Background Depression and anxiety disorders and symptoms are among the leading causes of disability and global disease burden in young people. Scalable, unified interventions are required to address subthreshold emotional symptoms in adolescents as a preventive strategy. This study evaluated the effectiveness...
E. Fonseca-Pedrero, Alfonso Pérez-Esteban, Adriana Díez-Gómez et al.· Psychological Medicine· 0 citations
The translation of evidence-based psychological treatments into accessible, real-world care remains a central challenge in global mental health implementation. Although approximately 3.4% of Chinese adults meet criteria for Major Depressive Disorder (MDD), only around 12% receive any form of treatment. Developing brief...
Nai-Hong Xu, Dong-Rong Zhao, Hao-Ke Li et al.· Cognitive Therapy and Resear...· 0 citations
Anxiety disorders are highly prevalent in childhood, and increasing demand for services highlights the need for scalable and accessible interventions. This pilot randomized controlled equivalence trial examined the feasibility and preliminary efficacy of a blended adaptation of the Unified Protocol for Children ("Emoti...
H. Moreira, Margarida Perdigão, D. Skvarc et al.· Child Psychiatry and Human D...· 0 citations
OBJECTIVES
Mindfulness is increasingly being implemented in child and adolescent therapy. However, little is known about its effectiveness in individual settings within a clinical outpatient context. We investigated the effects of session-introducing mindfulness interventions (IG-M) compared to session-introducing rela...
Julia Kalmar, Ines Baumann, Elena Schleiting et al.· Journal of Clinical Psycholo...· 0 citations
OBJECTIVE
This study evaluated the efficacy of Regulation-Focused Psychotherapy for Children (RFP-C), a manualized time-limited psychodynamic treatment for externalizing disorders targeting implicit emotion regulation.
METHOD
Eighty Turkish children (Mage = 8.53 years, 71.25% male) with externalizing disorders were r...
S. Halfon, Melike Albayrak, Maide Körlü Bulut et al.· Psychotherapy Research· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.