Sep 2026· INTERNATIONAL JOURNAL OF MATHEMATICS AND COMPUTER RESEARCH· Vol 14· 0 citations
Maternal and fetal healthcare
TL;DR
The findings show that interpretable machine learning can deliver reliable predictive performance even on small clinical datasets from resource-constrained settings, supporting proactive obstetric intervention and improved decision-making.
Abstract
Postpartum haemorrhage (PPH) is a leading cause of maternal morbidity and mortality worldwide, with a disproportionate burden in low-resource settings where timely diagnosis is often difficult. This study presents an interpretable AI-based early warning framework for predicting PPH using machine learning. A retrospective dataset of 223 anonymized obstetric records from Mpilo Central Hospital, Zimbabwe, was used for model development. Preprocessing involved missing-value imputation, outlier capping, feature engineering, and normalization, generating clinically relevant features such as labour duration in minutes, binary obstetric risk indicators, and a composite maternal risk score. Random Forest and Multilayer Perceptron (MLP) models were trained and evaluated on an 80:20 split. Random Forest achieved superior performance, with 86.67% accuracy, 89.47% precision, 80.95% recall, an F1-score of 85.00%, and ROC-AUC of 0.8730 for the PPH class. Labour duration and delivery method were the most influential predictors. SHAP (Shapley Additive Explanations) was used to enhance interpretability and clinical transparency. The findings show that interpretable machine learning can deliver reliable predictive performance even on small clinical datasets from resource-constrained settings, supporting proactive obstetric intervention and improved decision-making.
High-risk pregnancies are the main reason for high maternal and infant mortality and morbidity rates. Efforts to detect these pregnancies early are essential to ensure timely and targeted medical interventions. The objective of this study is to develop a pregnancy risk prediction model that combines machine learning al...
Gusrino Yanto, Sari Puspita· TEM Journal· 0 citations
Postpartum hemorrhage (PPH) is the leading cause of preventable maternal mortality worldwide. Emergency postpartum hysterectomy represents the ultimate life-saving intervention for refractory PPH but results in irreversible infertility and severe long-term maternal complications. Current clinical risk assessment reli...
Xin-Yi Yao, Can Yang, Lingyun Hu et al.· Scientific Reports· 0 citations
BACKGROUND
Preeclampsia remains a leading cause of maternal mortality, particularly in low-resource settings. We aimed to develop a dynamic prediction model accommodating repeated measurements for predicting adverse maternal outcomes in preeclampsia.
METHODS
We utilized data from 7283 women with preeclampsia from the...
Gui-You Yang, Tünde Montgomery-Csobán, G. Lunter et al.· HYPERTENSION· 0 citations
Early identification of patients at high risk of in-hospital mortality is a persistent challenge in clinical practice, particularly during infectious disease outbreaks such as COVID-19, when decisions must be made at the time of hospital admission using incomplete information. Although machine learning methods have bee...
V. Kunichik, O. Salykova· Herald of Kazakh-British tec...· 0 citations
Objective To develop and internally validate an explainable machine learning model for early mortality prediction in pediatric sepsis using routinely available clinical variables, to support clinical risk stratification and decision-making. Methods A total of 752 children with sepsis admitted to the Pediatric Intensive...
Hong-Mei Chen, Li-Nong Wang, Yan-Bing Fu et al.· Frontiers in Pediatrics· 0 citations
Hypertension is one of the major contributors for gravid women and unborn child’ death especially in the developing countries where access to innovative diagnostic technologies is not common. The study used explainable machine learning algorithm to predict hypertension risk using basic clinical attributes. Pregnant wom...
Olutola Agbelusi· Journal of Science, Technolo...· 0 citations
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MIT News · Artificial Intelligence· news.mit.eduNov 2, 2026
The MIT professors collaborated to identify the first AI-discovered antibiotic, a scientific breakthrough that is widely recognized as a milestone in AI-driven drug discovery.
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