Sep 2026· Network Modeling Analysis in Health Informatics and Bioinformatics· Vol 15· 0 citations· 130 references
TL;DR
Future studies should prioritize standardized analytical pipelines, multicenter validation cohorts, experimental confirmation of predicted ceRNA mechanisms, and integration with single-cell, spatial transcriptomic, and epitranscriptomic data to improve biomarker reproducibility and accelerate their clinical translation.
Background/Objectives: Colorectal cancer (CRC) is a leading cause of neoplasia-related morbidity and mortality worldwide and the first cause of cancer death in Mexico, where early detection remains a challenge, and reliable molecular biomarkers could support earlier diagnosis. Transcriptomic signatures for CRC have bee...
César de Jesús Tovar-Jácome, L. F. Jave-Suárez, Jesús García-Gómez et al.· Genes· 0 citations
An overview of recent progress in multi-omics approaches is provided and significant miRNA-, lncRNA-, and exosome-related biomarkers associated with the initiation, progression, and therapeutic response of breast cancer are emphasized.
Kamyar Bagheri, Amirhossein Saberi, Maryam Zand et al.· Cancer Treatment and Researc...· 0 citations
Convergent genetic, transcriptomic, and protein-level evidence prioritizes CDC16 as a GC-associated candidate tissue marker whose expression is closely linked to proliferative activity.
Fan Xue, Dao-Cheng Wu, Xu Zhang· International Journal of Bio...· 0 citations
Ovarian cancer (OC) is the most lethal gynecological malignancy, largely because non-specific symptoms contribute to advanced-stage diagnosis and poor prognosis, underscoring the need for improved non-invasive biomarkers. Circulating microRNAs (c-miRNAs) have emerged as promising candidates for OC detection, risk strat...
Karen Ayache, A. Vieira, S. Fragoso et al.· International Journal of Mol...· 0 citations
These results identify seven tissue-transcriptomic candidates with strong dataset-specific discriminative performance and provide a multidimensional biological framework warranting experimental validation and prospective clinical evaluation.
Zeynep Mutlu Coskun, Muhammet Coskun, Saime Sezer Sondaş· Current Issues in Molecular...· 0 citations
Abstract Introduction: Breast cancer (BC) remains a leading cause of cancer-related mortality among women worldwide. Despite advances in molecular diagnostics, reliable non-invasive biomarkers for early detection and disease staging remain limited. Circulating microRNAs (miRNAs) are promising epigenetic regulators invo...
A. Abdel-Hamed, Marina Barsom, Mahmoud M. Kamel et al.· Journal of Circulating Bioma...· 0 citations
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