Skip to content

A novel topical nitroglycerin-lidocaine combination for procedural pain management and rapid cannulation in neonates: results from a randomized controlled clinical trial

Jul 2026 · European Journal of Clinical Pharmacology · Vol 82 · 0 citations · 49 references
Medicine

TL;DR

Topical lidocaine/nitroglycerin 2% provided rapid analgesia and reduced repeated venipuncture attempts in neonates, offering a practical strategy for pain management in the neonatal intensive care unit (NICU).

View source

Similar papers

Open access Aug 2026

Efficacy of ethyl chloride topical anesthesia application on pain perception during intra-oral injections in children compared to benzocaine gel—a single-blind randomized controlled trial

Both anesthetic agents produced comparable physiological responses, self-reported experiences, and behavioral reactions during intra-oral local anesthetic injections in cooperative children aged 7–10 years, and the superiority trial did not reveal a statistically significant difference.

Nagah Abdelrahman, M. Al Halabi, M. Kowash et al. · 0 citations
Open access Aug 2026

Magnesium Sulfate vs. Lidocaine 2% Nebulization for Post-Operative Sore ThroatIncidence in Elective Laparoscopic Cholecystectomy under General Anesthesia

Objective: To compare the effectiveness of the two different preoperative nebulization, “Magnesium Sulphate” and “2% Lidocaine” for minimizing the frequency and intensity of post-procedural throat pain among individuals undergoing scheduled laparoscopic cholecystectomy managed with general anesthesia.Methods: A prospec...

Arqam Shaikh, Nuvair Zia, Ali Akram et al. · 0 citations
Open access 2026

Comparison of the wide-awake local anesthesia with no tourniquet (WALANT) technique with local anesthesia in chest tube placement procedures

Aim: Wide-awake local anesthesia with no tourniquet (WALANT) is increasingly used in surgical practice due to its safety profile, reduced resource requirements, and elimination of sedation. Although widely studied in hand surgery, its role in emergency thoracic procedures remains unclear. This study aimed to compare th...

Ayça Çalbay, A. Ulaş, S. Gur et al. · 0 citations
Open access Sep 2026

Efficacy and Safety of Intravenous Paracetamol Compared with Intramuscular Tramadol for Labor Analgesia: A Randomized Controlled Trial

Abstract Pain management is essential in labor. While regional analgesia is the gold standard, it often requires resources and expertise not widely available in low-resource settings. Intravenous paracetamol and intramuscular tramadol are potential alternatives, but their comparative efficacy and safety remain...

Uzoma Ogbonna-Onwukwe, J. A. Adebayo, A. Nweke et al. · 0 citations
Open access Oct 2026

Effectiveness of 0.5% Ropivacaine with Magnesium Sulfate versus 0.5% Ropivacaine Alone in Ultrasound-guided Supraclavicular Brachial Plexus Block: A Prospective Observational Study

Adding magnesium sulfate to 0.5% ropivacaine with magnesium sulfate did not significantly prolong the duration of postoperative analgesia, however, it was associated with reduced postoperative tramadol requirements and increased early sedation, while maintaining haemodynamic stability.

Priya Chandran, KS Santhi, T. Joseph · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.