In human subjects with DBS electrodes implanted in the VS and anterior limb of the internal capsule, electroencephalography recordings obtained during DBS ON and OFF conditions revealed a global suppression of theta activity, whose magnitude was related to effective connectivity.
Patterned brain stimulation is commonly employed to modulate brain circuits and treat neuropsychiatric disorders. Although widely used in clinical settings, there remains limited understanding of how stimulation alters neural oscillations and how these effects relate to baseline evoked network responses. To address thi...
Saachi Munot, Naryeong Kim, Yu-Hao Huang et al.· Journal of Neurophysiology· 0 citations
By identifying how stimulation frequency governs the mechanism of neural engagement and how behavioral state selectively gates brain-wide entrainment but not local inhibitory recruitment, the results provide a mechanistic foundation for designing targeted, reproducible neuromodulation strategies.
I. Rembado, Soo Yeun Lee, L. Marks et al.· bioRxiv· 0 citations
Deep brain stimulation (DBS) of the mesencephalic locomotor region (MLR) has been explored to treat gait disturbances. However, clinical outcomes of MLR-DBS have been disappointing overall, with only modest benefits in some individuals and unwanted effects, including anxiety, reported in others. Preclinical studies in...
Martina Wilhelm, J. Hartig, Teresa Christina Faupel et al.· bioRxiv· 0 citations
An exploratory trial-by-trial analysis revealed an overall effect of trial-by-trial brain state on TEP amplitudes, confirming successful engagement of the sensorimotor network.
Motahare Delbari, Christoph S. Herrmann, Christian Grefkes et al.· bioRxiv· 0 citations
This study provides the sham-controlled evidence that a single high-dose iTBS session induces specific neurophysiological modulation in the left DLPFC, and suggests that the rapid efficacy of SNT may stem from engaging these powerful compensatory mechanisms, thereby rapidly resetting the cortical Excitation/Inhibition...
S.-X. Wang, W. Chau, V.-W.-M. Lam et al.· International Journal of Neu...· 0 citations
Transcranial magnetic stimulation (TMS) is a fundamental tool for causal inference, but identical stimulation produces different outcomes depending on the instantaneous brain state, undermining interpretation and reproducibility. EEG-guided TMS studies to date have primarily addressed this by timing stimulation to loca...
Arianna Brancaccio, C. Miniussi· Clinical Neurophysiology· 1 citation
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