Aug 2026· Journal of Pharmaceutical Innovation· Vol 22· 0 citations· 28 references
TL;DR
Niosomal hesperidin-rich Citrus peel extract provides superior protection against TIR-induced oxidative and apoptotic injury compared with free hesperidin, likely due to enhanced stability, and support the use of nanocarrier-based delivery systems to improve the therapeutic potential of natural antioxidants in reproductive medicine.
It is suggested that DEX attenuates HFCS-induced liver injury through a multi-target mechanism involving suppression of oxidative damage, apoptosis, and inflammasome-associated pyroptotic signaling in young adult rats.
A. Elmas, H. Aşçı, M. Y. Tepebaşı et al.· International Journal of Mol...· 0 citations
HES and HES-PLGA-NPs were associated with multi-mechanistic protection against cisplatin-induced oxidative, inflammatory, apoptotic, and ferroptosis-associated damage in the testes, and may represent a promising nanoantioxidant candidate warranting further investigation for preserving male reproductive function during...
Mohammed A. Akeel, E. Elmorsy, Aly A. M. Shaalan et al.· Antioxidants· 0 citations
HSP may exert protective effects against DLM-induced testicular injury by modulating systemic oxidative status, apoptosis-associated signaling, and profibrotic gene expression.
RDP induces testicular dysfunction through oxidative-inflammatory and mitochondrial pathways, whereas EECS exerts protective effects via antioxidant and anti-inflammatory mechanisms, suggesting that EECS may be a promising agent against RDP-induced reproductive toxicity.
T. Olatunji, A. Odetayo, H. Abdulrahim et al.· JBRA Assisted Reproduction· 0 citations
Investigating the protective effects of OLE against ACR-induced reproductive toxicity in male and female rats indicates that OLE exerts a significant cytoprotective effect through its antioxidant and anti-apoptotic properties, with the extent of protection varying across tissue types.
Nevzat Saat, E. Aksu, M. Tatar et al.· Journal of Molecular Histolo...· 0 citations
