Brain dynamics exhibit scale-dependent reversibility during consciousness transitions

Spatial spectral narrowing in the corticothalamic neural field model across consciousness states

Evolution and Reorganization of the Hierarchical Brain-wide Neuronal Network Through Anesthesia.

Local and interregional thalamocortical dynamics show temporally dissociable changes during propofol induced loss of consciousness.

Whether propofol-induced loss of consciousness (LOC) reflects a single thalamocortical transition or involves temporally dissociable local and interregional dynamics remains unclear. Using stereo-electroencephalography recordings from the anterior nucleus of the thalamus, prefrontal cortex, and temporal cortex during a...

Brain network and oscillation dynamics mirror the inward and outward orientation of spontaneous thought

These multimodal findings reveal distinct neural signatures of spontaneous experience and demonstrate that coordinated large-scale network dynamics and alpha-band oscillations track the natural alternation between inward and outward focus in the human mind.

Excitation-inhibition balance dynamics across brain networks during naturalistic behavior

A dual-color multisite spectrally- resolved fiber photometry platform is developed to simultaneously record genetically defined E and I populations across four cortical regions and identifies transient E-I imbalance as a normal feature of naturalistic behavior, with implications for understanding network dysfunction in...

Tensor decomposition reveals discrete cortical reorganization under graded propofol anesthesia

Although propofol-induced anesthesia is known to suppress consciousness by promoting low-frequency frontal oscillations through thalamocortical circuits, a comprehensive understanding of its whole-brain coupling feature set remains elusive. Specifically, the global reorganization of nonlinear cross-frequency coupli...