A pragmatic approach to combat lipotoxicity in HepG2 cells: Engineering of curcumin loaded polydopamine coated Zn-MOF
Polydopamine-coated Zn-MOF-based curcumin delivery is a promising approach for further investigation of NAFLD/NASH, and curcumin activity in an in vitro HepG2 lipotoxicity model is improved by reducing oxidative stress and lipid accumulation while supporting PREP inhibition and favorable gene expression changes.