Author

A. Deitchman

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Open access Sep 2026

SARS-CoV-2-specific monoclonal antibody AER002 in Long COVID: an exploratory randomized phase 2a mechanistic trial

Persistence of SARS-CoV-2 has been proposed as a biological driver of Long COVID, a disabling chronic illness with no proven treatments. We conducted an exploratory, placebo-controlled, double-blind, 2:1 randomized mechanistic trial (NCT05877508) of the SARS-CoV-2-specific monoclonal antibody AER002 in 36 participa...

M. Peluso, Dylan Ryder, T. Dalhuisen et al. · Nature Communications · 0 citations

Open access Sep 2026

A mechanistic basis for CD8+ T cell expansion sensitivity as a predictor of HIV post-treatment control

The results provide a mechanistic explanation why both Ki-67+ responding CD8+ T cells and their TCF-1-expressing subset predict post-treatment control, linking clinical correlation to its underlying cause and highlighting Ki-67 and TCF-1 as potential early biomarkers of HIV immunotherapy success.

Tin Phan, Nicole Pagane, Jasmine A. F. Kreig et al. · bioRxiv · 0 citations

Aug 2026

Multiomic and Spatial Profiling of Colorectal Tissue Reveals Viral Persistence and Immune Dysregulation in Long COVID

A tissue-based transcriptional environment in which SARS-CoV-2 activates innate myeloid immune signaling, driving chronic inflammation while simultaneously downregulating pathways responsible for immune-mediated clearance of infected cells is identified, including antigen presentation, phagocytosis, cytotoxic immune ce...

B. LaFranchi, David P. Maison, J. Vinden et al. · bioRxiv · 0 citations