Review
Open access
Jul 2026
Targeting molecular and genetic pathways driving tumorigenesis for precision therapy in colorectal cancer
ABSTRACT Colorectal cancer (CRC) remains a major global health challenge and a leading cause of cancer-related mortality worldwide. Central to its pathogenesis is the dysregulation of interconnected signal transduction networks that govern cellular proliferation, survival, differentiation, apoptosis, and immune modulat...
Allison S Doermann, Adi Caspi, Andrew E. Evans et al.
· Cancer Biology & Therapy · 0 citations