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1,554 papers
This review focuses primarily on the current state of CRISPR-based epigenome editing systems, including acetyltransferases, demethylases, DNA methyltransferases, and deacetylases, and their applications in crop improvement research and critically evaluates their mechanisms in rewriting epigenetic regulatory information...
Genetically modified Plasmodium falciparum parasites expressing transgenes such as fluorescent markers are crucial tools for malaria research. However, current reporter lines often rely on integrated transgene constructs that disrupt the coding sequence of a native gene, potentially affecting progression in the life cy...
Biotechnology has evolved from ancient fermentation practices and the domestication of plants and animals into a multidisciplinary field that integrates molecular biology, genetics, engineering, and computational sciences.This review presents a comprehensive overview of the historical evolution of biotechnology, highli...
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Clade V-MLOs are associated with powdery mildew susceptibility in several plants. In grapevine, four MLO genes (MLO3, MLO4, MLO13, and MLO17) belong to clade V and have been studied to determine their contribution to susceptibility to Erysiphe necator (Grape Powdery Mildew—GPM). Using somatic embryogenesis to generate...
Selection-marker-assisted homology-directed repair (HDR) efficiently edits coding sequence termini but is poorly suited for internal exons. Here, we developed artificial reporter intron-based HDR (ARI-HDR), which inserts a selectable intron into target exons to enable precise internal-exon editing. Although designed fo...
Plants are continuously exposed to an increasingly complex combination of environmental constraints rather than to individual stresses occurring in isolation. Drought, heat, salinity, flooding, chilling, high light, ultraviolet-B (UV-B) radiation, nutrient imbalance, heavy metals and atmospheric pollutants can occur si...
The hearing aids and cochlear implants were extremely effective in restoring auditory function; however, none of these devices provides any cure to the underlying molecular disease. Recently there has been an unprecedented advancement in the multiple fields including genomic diagnostics, viral vector engineering, metho...
Precision plant breeding seeks to link biological target discovery with the development and evaluation of useful alleles in crop improvement. Genome-editing platforms, including CRISPR–Cas nucleases, base editors, prime editors, multiplex editing and cis-regulatory editing, enable targeted genomic alterations; however,...
Maize (Zea mays L.) is an important cereal crop, but the application of genetic transformation in tropical germplasm is constrained by genotype-dependent regeneration and the limited availability of suitable explants. The present study evaluated mature seed-derived split internodes as an alternative explant source for...
General Science
A Blog post by NVIDIA on Hugging Face
Zero-knowledge proofs can verify computing results without rerunning workloads or exposing sensitive data. Magnetar helps bring them into the mainstream with support for standard programming languages, major speed gains, and quantum-resistant security. The post Proof-based general-purpose computing with Magnetar appeared first on Microsoft Research.
General Science
General Science
GPT-Lab
· gpt-lab.eu
Oct 8, 2026
Exploring how generative AI could make machine vision more accessible to businesses. The post GenEye in a Box: Making Machine Vision Something You Can Just Ask For appeared first on GPT-Lab.
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