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A. Lupták

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Open access Oct 2026

Substrate energetics in non-templated DNA synthesis by terminal deoxynucleotidyl transferase

Abstract DNA polymerases typically use deoxyribonucleoside triphosphates (dNTPs) for DNA synthesis, yet the contribution of the γ-phosphate to catalysis remains unclear. Here, we examine the role of substrate energetics in enzyme-catalyzed polymerization using a fidelity-independent model polymerase, terminal deoxynucl...

Katrina Mogannam, A. Lupták · 0 citations
#protein folding Open access Oct 2026

A miniature bioluminescent platform for imaging structured RNAs

A miniaturized bioluminescent platform for RNA imaging that employs a compact RNA tag that assembles luciferase fragments upon binding of monomeric RNA-binding proteins (RNA lanterns) and establishes a miniaturized bioluminescent platform for imaging a broad range of RNA targets in living systems.

Christelle E. T. Chan, Erin B. Fuller, Claire C. Chen et al. · 0 citations

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