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Review Open access Oct 2026

RIFM at 60: Six Decades of Advancing Fragrance Safety Through Research, Risk Assessment, and Scientific Innovation.

Fragrance safety assessment requires the integration of toxicology, exposure science, and risk assessment to evaluate fragrance ingredients used across all consumer products. Since 1966, the Research Institute for Fragrance Materials (RIFM), an independent, international, non-profit scientific organization, has been ad...

A. M. Api · 0 citations
Review Open access Oct 2026

An Overview of In Vitro Genotoxicity Testing Strategies for Fragrance Materials: Addressing False Positives and Advancing Non-Animal Approaches.

The European Union's ban on in vivo genotoxicity testing for cosmetic ingredients (Directive 2003/15/EC), followed by the Scientific Committee on Consumer Safety (SCCS) 7th amendment, has created an urgent need for robust, non-animal genotoxicity testing strategies. Standard regulatory in vitro assays - including the A...

Yax Thakkar, D. Botelho, A. M. Api · 0 citations

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