Open access
Sep 2026
The obesity associated BDNF intron-3 cis-regulatory element, BE5.1, modulates the effects of early-life stress on weight gain, anxiety and gene expression in a sex-dependent manner
Results suggest that the BE5.1CRE acts as a buffer element that protects against the maladaptive effects of MS on gene expression and later life behaviours in a sex-dependent manner.
A. McEwan, Joseph Morgan, Greg Hutchings et al.
· bioRxiv · 0 citations