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Author

A. Quattrone

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#protein folding Oct 2026

A preanalytical quality indicator framework for automated extracellular vesicle separation

Abstract Objectives Clinical translation of extracellular vesicle (EV)-based diagnostics is constrained by preanalytical variability in separation workflows. We developed a preanalytical quality indicator framework for automated EV separation, anchored to IFCC, EFLM, and MISEV2023 standards. This proof-of-concept study...

A. M. Zimbo, V. Crapella, S. Mimmi et al. · 0 citations
Open access Sep 2026

MIND-Based Cortical Similarity Networks reveal distinct Cortical Alterations in Motor Subtypes of Parkinson's Disease.

Findings indicate that individualized morphometric similarity networks capture a dimension of PD heterogeneity beyond conventional motor phenotypes and may provide a biologically informed framework for patient stratification.

M. Bianco, Camilla Calomino, F. Novellino et al. · 0 citations
Review Sep 2026

Glial fibrillary acidic protein in progressive supranuclear palsy: A systematic review and meta-analysis.

Mean blood GFAP concentrations are higher in clinically diagnosed PSP than in healthy controls, although the biological basis and disease specificity of this finding remain uncertain, and GFAP should not be considered a stand-alone diagnostic marker.

G. Magro, Vincenzo Laterza, A. Mechelli et al. · 0 citations
Open access Aug 2026

Structural, functional and neurochemical imaging mapping of non-motor symptoms in Parkinson’s disease

It is demonstrated that the brain networks associated with RBD, depression and anxiety non-motor symptoms were largely overlapping, involved the attention networks and were spatially aligned with the noradrenergic system, suggesting that these symptoms may have shared neurobiological substrates.

Chiara Camastra, Aldo Quattrone, A. Quattrone · 0 citations
Open access Oct 2026

Patient-Reported Complications and Outcomes of General, Central Neuraxial, and Peripheral Regional Anesthesia in Charcot-Marie-Tooth Disease.

Anesthesia-related complications are not reported more frequently in patients with CMT compared with controls, however, longitudinal studies incorporating objective clinical assessments and detailed information on anesthetic agents are warranted.

A. Bertini, Marco Gemma, Fiore Manganelli et al. · 0 citations
Review Open access Jul 2026

Multiple system atrophy: cure and care.

Bridging advances in pathophysiology with patient-centred care will be essential for improving outcomes in MSA, and advances in fluid biomarkers and multimodal imaging are expected to facilitate earlier detection, improve diagnostic accuracy, and provide more robust tools for monitoring disease progression.

J. Buonocore, Bianca Calió, Fabian Leys et al. · 0 citations
Open access Jul 2026

Morphometric Inverse Divergence Networks Combined with HYDRA Identify Parkinson’s Disease Subtypes with Distinct Transcriptomic and Serum Biomarker Profiles

Two biologically distinct PD subtypes are identified with divergent molecular architecture and systemic neurodegeneration beyond conventional motor phenotyping beyond conventional motor phenotyping.

M. Bianco, Camilla Calomino, Maria Celeste Bonacci et al. · 0 citations

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