An Overview of Programmable Epigenetic Editing Based on CRISPR Tools for Gene Expression Regulation.
Epigenetic regulation provides a dynamic and reversible layer of gene control that functions independently of changes in DNA sequence, primarily mediated by DNA methylation, histone modifications, and higher-order chromatin organization. Aberrant epigenetic states contribute to a wide range of human diseases. However,...
Marija Djordjevič, S. Dinić, Ana Sarič et al.
· Methods in molecular biology · 0 citations