Beyond Acid Suppression: Vonoprazan as a Multi-Target Modulator in Experimental Colitis from Oxidative Stress to Mitochondrial Rescue.
Ulcerative colitis (UC); as one of the inflammatory bowel diseases (IBD), arises from chronic inflammation of the intestinal tract. In this study, we addressed the possible protective mechanisms of vonoprazan, as a potassium-competitive acid blocker, on dextran sulfate sodium (DSS)-mediated UC. Therefore, male BALB-c m...