Author

Abdulelah Alhazza

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#gene editing Open access Sep 2026

Charge modulation of peptide/nucleic acid complexes: an anionic additive enhances gene silencing and CRISPR/Cas9 editing by promoting intracellular nucleic acid release

Small interfering RNA (siRNA) and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated Protein 9 (Cas9) complexes are effective approaches to temporarily downregulate protein expression via post-transcription RNA interference or permanently altering protein expression via editing gen...

Abdulelah Alhazza, Sorour Khayyatnejad Shoushtari, Hasan Uludağ et al. · Frontiers in Nanotechnology · 0 citations

Open access Aug 2026

Sabinene attenuates inflammation and oxidative stress in CFA-induced arthritis: In vivo and in silico evidence implicating TLR4/NLRP3/NF-κB signaling.

Findings support a prophylactic protective effect of sabinene against CFA-induced arthritis associated with reduced inflammation, improved antioxidant status, and modulation of inflammasome-related gene expression.

Kanwal Asif, Ambreen Malik Uttra, Arham Shabbir et al. · Biomolecules & biomedicine · 0 citations