Explainable attention-based multi-omics fusion with protein language models for CML-versus-control classification and biomarker discovery
Chronic Myeloid Leukemia (CML) is a well-defined hematological malignancy driven principally by the BCR::ABL1 fusion oncogene and aberrant tyrosine kinase signaling. Computational methods to predict leukemia suffer from the limitation of using single-modality data or black-box models, which cannot adequately incorporat...