Open access
Oct 2026
Epstein-Barr virus co-opts ADAR1 to evade PKR activation of the integrated stress response in nasopharyngeal carcinoma
It is discovered that Epstein-Barr virus (EBV), the oncogenic driver of nasopharyngeal carcinoma (NPC), requires ADAR1 both to maintain latent infection and for lytic reactivation by preventing PKR-mediated ISR activation.
Shane Wiebe, Ming-Guan Ng, Adlina Roslan et al.
· bioRxiv · 0 citations