Akshay Singh Rekhraj

The Vascular Genome as a Therapeutic Target: A Systematic Review of CRISPR-based Gene Editing In Vascular Disease

CRISPR/Cas9-mediated genome editing of these targets modulates critical biological pathways, resulting in enhanced nitric oxide production, improved endothelial function and angiogenesis, reduced oxidative stress and inflammatory signaling, decreased lipid accumulation and plaque formation, restoration of vascular smoo...