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Review Open access 2026

Cholangiocarcinoma in 2026: Pathophysiology, Diagnostic Advances, and Evolving Therapeutic Landscape—A Narrative Review

Cholangiocarcinoma (CCA) is a heterogeneous malignancy of the biliary epithelium, classified into intrahepatic, perihilar, and distal subtypes with distinct molecular signatures, risk factor profiles, and clinical behavior. This narrative review synthesizes current understanding of CCA pathophysiology, established and...

Elmukhtar Habas, Aml Habas, Amnna Ali Rayani et al. · 0 citations
Review Open access 2026

Post-Kidney Transplantation Malignancy: Risk, Pathogenesis, and Management

The rising incidence of cancer in kidney transplant patients poses a significant barrier to longterm patient and graft survival. Immunosuppression is a primary component in cancer risk, although the interaction of recipient characteristics, viral oncogenesis, and donor-related factors complicates risk assessment. Curre...

Elmukhtar Habas, Amnna Rayani, Aml Habas et al. · 0 citations
Review Open access 2026

Cardio-Reno-Cardiac Syndrome, Classification, Pathophysiology and Clinical Implications: Review—Part 6

Type 5 cardio-renal syndrome (CRS), cardio-reno-cardiac syndrome (CRCS), is a condition secondary to systemic diseases that usually leads to acute or chronic dysfunction of the heart or kidney, which causes dysfunction of the other organ. Different pathophysiological mechanisms and factors affecting CRCS development, s...

Elmukhtar Habas, Amnna Rayani, Ala Habas et al. · 0 citations

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