Oct 2026
Isorhoifolin attenuates cadmium-induced hepatotoxicity by modulating TLR4/MyD88/TRAF6/NF-κB and Nrf2/Keap1 pathways: a biochemical and histological study
Results showed that Cd exposure substantially downregulated BCL-2 mRNA expression, upregulated the apoptotic proteins BAX and CASPASE-3, and caused severe histopathological damage, but IRF attenuated all the above-mentioned damages and preserved hepatic tissue architecture.
Naila Ghafoor, Amna Munir, Moazama Batool et al.
· Molecular Biology Reports · 0 citations